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Baclofen
Clinical data
Trade namesLioresal, Liofen, Gablofen, others
AHFS/Drugs.comMonograph
License dataUS   FDA: Baclofen
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, intrathecal
ATC codeM03BX01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityWell-absorbed
Protein binding30%
Metabolism85% excreted in urine/faeces unchanged. 15% metabolised by deamination
Elimination half-life1.5 to 4 hours
ExcretionRenal (70–80%)

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. Garay RP, Bayle FJ, Llorca PM, Lancon C, Thomas G, Hameg A, 2004. QTc interval prolongation in the ..

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