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Clinical data
Pronunciation/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade namesViagra, Revatio, others
License dataEU  EMA:  by INN, US   FDA: Sildenafil
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (tablets), IV
ATC codeG04BE03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: P (Pharmacy medicines) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability41% (mean) [1]
Protein binding~96%
MetabolismLiver: CYP3A4 (major route), CYP2C9 (minor route)
MetabolitesN -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life3–4 hours
ExcretionFeces (~80%), urine (~13%) [2]

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Active substancesassurans
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    Sildenafil should be used in pregnant women only goodrx coupon sildenafil 100 mg clearly needed or power bull 150 sildenafil generic for best price. Women with PAH should inform their clinician if they are or plan to become pregnant prior to initiation of treatment with sildenafil.his metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug.

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    Severe cardiovascular events have been reported temporally in goodrx coupon sildenafil 100 mg with sildenafil use, but the contribution of the drug to a fatal outcome is unclear.Some people may also have ringing in their ears tinnitus or dizziness. If you havethese symptoms, stop taking VIAGRA and contact a doctor right away have or have had heart problems such as a heart attack, rregular goodrx coupon sildenafil 100 mg, angina, chest pain, narrowing of the aortic valve, or heart failure have problems with your blood cells such as sickle cellanemia, multiple myeloma, or leukemia Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, nd herbal supplements.

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