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Sildenafil
Clinical data
Pronunciation/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade namesViagra, Revatio, others
AHFS/Drugs.comMonograph
MedlinePlusa699015
License dataEU  EMA:  by INN, US   FDA: Sildenafil
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (tablets), IV
ATC codeG04BE03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: P (Pharmacy medicines) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability41% (mean) [1]
Protein binding~96%
MetabolismLiver: CYP3A4 (major route), CYP2C9 (minor route)
MetabolitesN -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life3–4 hours
ExcretionFeces (~80%), urine (~13%) [2]

Neuropsychological and Behavioral Changes in Asthmatic Children. Treated With Beclomethasone Dipropionate Versus Theophylline. Bruce G. Bender, PhD* ,‡ ...

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Active substancesildenafil
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By Dr Robert R Montserrat MD

Dr. Robert R Montserrat, MD is a Obstetrician / Gynecologist (OBGYN) - Hospice & Palliative Medicine practicing in Little Silver, NJ He has not yet shared a personalized biography with Doctor.com.

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Obstetrician / Gynecologist (OBGYN) - Hospice & Palliative Medicine

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