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Watch Daily Interviews With Leading Experts WARNINGS: Women who are pregnant must not use isotretinoin. Women must avoid becoming pregnant while taking this medication. Isotretinoin (accutane) packaging 10 mg 10 package quantity.

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Isotretinoin
Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), others [1]
AHFS/Drugs.comMonograph
MedlinePlusa681043
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVariable
Protein binding99.9%
MetabolismHepatic
Elimination half-life10–20 hours
ExcretionRenal and fecal

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One-fifth 18. of children reported no adverse reactions during the supplement period. Cheilitis was the most commonly reported adverse reaction, affecting 78 of products, followed by eczema and anxiety, seen in 12 each.

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