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Following abrupt or tapered duloxetine capsule 60 mg in placebo-controlled clinical trials, the following symptoms occurred at 1% or greater and at a significantly higher rate in duloxetine-treated patients compared to those discontinuing from placebo: dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, insomnia, anxiety, hyperhidrosis, and fatigue.Conversely, at least 5 days should be allowed after stopping DRIZALMA Sprinkle before starting an MAOI intended to treat psychiatric disorderssee CONTRAINDICATIONS, WARNINGS AND PRECAUTIONS.

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Adverse Reactions Reported as Reasons for Discontinuation of Treatment in Adult Placebo-Controlled Trials Adverse Reactions Occurring at an Incidence of 5% or More Among Duloxetine Delayed-Release Capsules-Treated Patients in Adult Placebo-Controlled Trials Table 2 gives the incidence of treatment-emergent adverse reactions in placebo-controlled trials for approved indications that occurred in 5% or more of duloxetine hcl 60mg ec caps treated duloxetine hcl 60mg ec cap duloxetine delayed-release capsules and with an incidence greater than placebo.

a The inclusion of an event in the table is determined based on the percentages before rounding; however, the percentages displayed in the table are rounded to the nearest integer.1-92.

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Efficacy of duloxetine for this indication has been duloxetine hcl 60 mg capsule dr by 3 placebo-controlled trials of 9-10 weeks' duration in outpatient settings in adults who met DSM-IV criteria for generalized anxiety disorder.

In these studies, patients receiving duloxetine 60-120 mg daily had greater improvements in the Hamilton anxiety scale HAM-A total score and the Sheehan Disability Scale SDS global functional impairment score than did patients receiving placebo.The safety of doses above 120 mg once daily has not been evaluatedsee Clinical Studies.

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